HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalyl chloride → 5-Methoxy-2-nitrobenzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 5-Methoxy-2-nitrobenzoic acid | HCID 339209 | — |
| Catalyst | Dimethylformamide | HCID 6228 | — |
| Product | 5-Methoxy-2-nitrobenzoyl chloride | HCID 12511553 | — |
Reaction Steps
A mixture of 5-methoxy-2-nitrobenzoic acid (15.8 g, 0.08 mol), oxalyl chloride (25 g, 0.197 mol) and N,N-dimethylformamide (2 drops) is stirred at reflux for 4 hours, cooled, stirred at room temperature under nitrogen for several days and concentrated in vacuo to give the title product as a yellow oil which is identified by 1HNMR spectral analysis.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05519133 |
| Source dataset | uspto-grants-1996_05 |
| ORD ID | ord-9a17cb54396d4d32a732003fbfbd032a |
| Source note | uspto-grants-1996_05 |