Sodium Hydroxide → HCID 57101615, compound

HRID 440584Notes

Reaction equation

HRID 440584 reaction equation
[CH2:1]([C:5]1[N:9]([CH2:10][C:11]2[CH:16]=[CH:15][C:14]([O:17][CH:18]([C:25]([O:27]CC)=[O:26])C3C=CC=CC=3)=[CH:13][CH:12]=2)[C:8]2[CH:30]=[C:31]([N:34]([CH2:41]C(N)=O)C3CCCCC3)[CH:32]=[CH:33][C:7]=2[N:6]=1)[CH2:2][CH2:3][CH3:4].[OH-:45].[Na+]>C(O)C>[CH2:1]([C:5]1[N:9]([CH2:10][C:11]2[CH:16]=[CH:15][C:14]([O:17][CH:18]([C:25]([OH:27])=[O:26])[C:15]3[CH:14]=[CH:13][CH:12]=[CH:11][CH:16]=3)=[CH:13][CH:12]=2)[C:8]2[CH:30]=[C:31]([N:34]([CH3:41])[C:5]([NH:6][CH:7]3[CH2:8][CH2:30][CH2:31][CH2:32][CH2:33]3)=[O:45])[CH:32]=[CH:33][C:7]=2[N:6]=1)[CH2:2][CH2:3][CH3:4]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 86749501HCID 86749501, compound

Product 1

HCID 57101615HCID 57101615, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Prepared analogously to Example 1b from 2-n-butyl-1-[4-[(α-ethoxycarbonyl)benzyloxy]benzyl]-6-(N-cyclohexyl-aminocarbonylmethylamino)benzimidazole and 1N sodium hydroxide solution in ethanol.

Sources & evidence

ORD record
ord-8b3189701e8c4e319dfd6f3d8df859ac
Source dataset
uspto-grants-1996_05
Patent number
US05519138

Reaction notes

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