Sodium Hydroxide → HCID 22407358, compound

HRID 440586Notes

Reaction equation

HRID 440586 reaction equation
[CH2:1]([C:4]1[N:18]([CH2:19][C:20]2[CH:25]=[CH:24][C:23]([O:26][CH:27]([C:34]([O:36]CC)=[O:35])[C:28]3[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=3)=[CH:22][CH:21]=2)[C:7]2=[N:8][C:9]([NH:12][C:13](=[O:17])[CH:14]([CH3:16])[CH3:15])=[CH:10][CH:11]=[C:6]2[N:5]=1)[CH2:2][CH3:3].[OH-].[Na+]>C(O)C>[CH2:1]([C:4]1[N:18]([CH2:19][C:20]2[CH:21]=[CH:22][C:23]([O:26][CH:27]([C:34]([OH:36])=[O:35])[C:28]3[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=3)=[CH:24][CH:25]=2)[C:7]2=[N:8][C:9]([NH:12][C:13](=[O:17])[CH:14]([CH3:15])[CH3:16])=[CH:10][CH:11]=[C:6]2[N:5]=1)[CH2:2][CH3:3]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 22407489HCID 22407489, compound

Product 1

HCID 22407358HCID 22407358, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Prepared analogously to Example 1b from 2-n-propyl-5-(2-methylpropionylamino)-3-[4-[(α-ethoxycarbonyl)benzyloxy]benzyl]imidazo[4,5-b]pyridine and 1N sodium hydroxide solution in ethanol.

Sources & evidence

ORD record
ord-b6ee5b0cfd6b43da9c5a9684f2cce41f
Source dataset
uspto-grants-1996_05
Patent number
US05519138

Reaction notes

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