Sodium Hydroxide → HCID 22407558, compound

HRID 440590Notes

Reaction equation

HRID 440590 reaction equation
[CH2:1]([C:5]1[N:6]([CH2:13][C:14]2[CH:19]=[CH:18][C:17]([O:20][CH2:21][CH2:22][CH:23]3[CH2:28][CH2:27][CH2:26][CH2:25][CH:24]3[C:29]([O:31]C)=[O:30])=[CH:16][CH:15]=2)[C:7]([Cl:12])=[C:8]([CH2:10][OH:11])[N:9]=1)[CH2:2][CH2:3][CH3:4].[OH-].[Na+]>C(O)C>[CH2:1]([C:5]1[N:6]([CH2:13][C:14]2[CH:15]=[CH:16][C:17]([O:20][CH2:21][CH2:22][CH:23]3[CH2:28][CH2:27][CH2:26][CH2:25][CH:24]3[C:29]([OH:31])=[O:30])=[CH:18][CH:19]=2)[C:7]([Cl:12])=[C:8]([CH2:10][OH:11])[N:9]=1)[CH2:2][CH2:3][CH3:4]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 22407398HCID 22407398, compound

Product 1

HCID 22407558HCID 22407558, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Prepared analogously to Example 1b from 2-n-butyl-4-hydroxymethyl-5-chloro-1-[4-[(1-methoxycarbonyl-2-cyclohexyl)ethoxy]benzyl]imidazole and 1N sodium hydroxide solution in ethanol.

Sources & evidence

ORD record
ord-c87d729cfa8942fbbc894759d7db21b4
Source dataset
uspto-grants-1996_05
Patent number
US05519138

Reaction notes

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