Sodium Hydroxide → HCID 22407332, compound

HRID 440593Notes

Reaction equation

HRID 440593 reaction equation
[CH2:1]([C:5]1[N:28]([CH2:29][C:30]2[CH:35]=[CH:34][C:33]([O:36][CH:37]([C:44]([O:46]CC)=[O:45])[C:38]3[CH:43]=[CH:42][CH:41]=[CH:40][CH:39]=3)=[CH:32][CH:31]=2)[C:8]2=[N:9][C:10]([CH3:27])=[C:11]([N:13]3[CH2:18][CH2:17][CH2:16][N:15]([CH2:19][C:20]4[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=4)[C:14]3=[O:26])[CH:12]=[C:7]2[N:6]=1)[CH2:2][CH2:3][CH3:4].[OH-].[Na+]>C(O)C>[CH2:1]([C:5]1[N:28]([CH2:29][C:30]2[CH:31]=[CH:32][C:33]([O:36][CH:37]([C:44]([OH:46])=[O:45])[C:38]3[CH:39]=[CH:40][CH:41]=[CH:42][CH:43]=3)=[CH:34][CH:35]=2)[C:8]2=[N:9][C:10]([CH3:27])=[C:11]([N:13]3[CH2:18][CH2:17][CH2:16][N:15]([CH2:19][C:20]4[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=4)[C:14]3=[O:26])[CH:12]=[C:7]2[N:6]=1)[CH2:2][CH2:3][CH3:4]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 22407522HCID 22407522, compound

Product 1

HCID 22407332HCID 22407332, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Prepared analogously to Example 1b from 2-n-butyl-3-[4-[(α-ethoxycarbonyl)benzyloxy]benzyl]-5-methyl-6-(3-benzyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinon-1-yl)-imidazo[4,5-b]pyridine and 2N sodium hydroxide solution in ethanol.

Sources & evidence

ORD record
ord-31b33ffb933d4c0fb03840c05bf4a409
Source dataset
uspto-grants-1996_05
Patent number
US05519138

Reaction notes

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