Sodium Hydroxide → HCID 53735396, compound

HRID 440604Notes

Reaction equation

HRID 440604 reaction equation
[CH2:1]([C:4]1[N:8]([CH2:9][C:10]2[CH:15]=[CH:14][C:13]([O:16][CH:17]([C:25]([O:27]CC)=[O:26])[C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=3[Cl:24])=[CH:12][CH:11]=2)[C:7]2[CH:30]=[CH:31][CH:32]=[C:33]([CH3:34])[C:6]=2[N:5]=1)[CH2:2][CH3:3].[OH-].[Na+]>C(O)C>[CH2:1]([C:4]1[N:8]([CH2:9][C:10]2[CH:11]=[CH:12][C:13]([O:16][CH:17]([C:25]([OH:27])=[O:26])[C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=3[Cl:24])=[CH:14][CH:15]=2)[C:7]2[CH:30]=[CH:31][CH:32]=[C:33]([CH3:34])[C:6]=2[N:5]=1)[CH2:2][CH3:3]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 53809995HCID 53809995, compound

Product 1

HCID 53735396HCID 53735396, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Prepared analogously to Example 1b from 2-n-propyl-4-methyl-1-[4-[(α-ethoxycarbonyl)-2-chlorobenzyloxy]-benzyl]benzimidazole and 2N sodium hydroxide solution in ethanol.

Sources & evidence

ORD record
ord-3f788c30e9a443bbbee18477e1548db1
Source dataset
uspto-grants-1996_05
Patent number
US05519138

Reaction notes

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