Sodium Hydroxide → HCID 22407427, compound

HRID 440605Notes

Reaction equation

HRID 440605 reaction equation
[CH2:1]([C:5]1[N:20]([CH2:21][C:22]2[CH:27]=[CH:26][C:25]([O:28][CH:29]([C:36]([O:38]CC)=[O:37])[C:30]3[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=3)=[C:24]([O:41][CH3:42])[CH:23]=2)[C:8]2=[N:9][C:10]([CH3:19])=[C:11]([NH:13][C:14]([N:16]([CH3:18])[CH3:17])=[O:15])[CH:12]=[C:7]2[N:6]=1)[CH2:2][CH2:3][CH3:4].[OH-].[Na+]>C(O)C>[CH2:1]([C:5]1[N:20]([CH2:21][C:22]2[CH:27]=[CH:26][C:25]([O:28][CH:29]([C:36]([OH:38])=[O:37])[C:30]3[CH:31]=[CH:32][CH:33]=[CH:34][CH:35]=3)=[C:24]([O:41][CH3:42])[CH:23]=2)[C:8]2=[N:9][C:10]([CH3:19])=[C:11]([NH:13][C:14]([N:16]([CH3:17])[CH3:18])=[O:15])[CH:12]=[C:7]2[N:6]=1)[CH2:2][CH2:3][CH3:4]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 22407539HCID 22407539, compound

Product 1

HCID 22407427HCID 22407427, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Prepared analogously to Example 1b from 2-n-butyl-3-[4-[(α-ethoxycarbonyl)benzyloxy]-3-methoxybenzyl]-5-methyl-6-dimethylaminocarbonylamino-imidazo[4,5-b]pyridine and 2N sodium hydroxide solution in ethanol.

Sources & evidence

ORD record
ord-2b2fbae12e2a408c8b5e37170bbbb7c1
Source dataset
uspto-grants-1996_05
Patent number
US05519138

Reaction notes

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