Sodium Hydroxide → HCID 22407568, compound

HRID 440607Notes

Reaction equation

HRID 440607 reaction equation
[CH2:1]([C:5]1[N:9]([CH2:10][C:11]2[CH:16]=[CH:15][C:14]([O:17][CH:18]([C:25]([O:27]CC)=[O:26])[C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)=[CH:13][CH:12]=2)[C:8]2[CH:30]=[C:31]([NH:35][C:36]([C:38]([CH3:41])([CH3:40])[CH3:39])=[O:37])[CH:32]=[C:33]([CH3:34])[C:7]=2[N:6]=1)[CH2:2][CH2:3][CH3:4].[OH-].[Na+]>C(O)C>[CH2:1]([C:5]1[N:9]([CH2:10][C:11]2[CH:12]=[CH:13][C:14]([O:17][CH:18]([C:25]([OH:27])=[O:26])[C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)=[CH:15][CH:16]=2)[C:8]2[CH:30]=[C:31]([NH:35][C:36]([C:38]([CH3:39])([CH3:41])[CH3:40])=[O:37])[CH:32]=[C:33]([CH3:34])[C:7]=2[N:6]=1)[CH2:2][CH2:3][CH3:4]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 22407451HCID 22407451, compound

Product 1

HCID 22407568HCID 22407568, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Prepared analogously to Example 1b from 2-n-butyl-4-methyl-1-[4-[(α-ethoxycarbonyl)benzyloxy]benzyl]-6-tert.butylcarbonylamino-benzimidazole and 2N sodium hydroxide solution in ethanol.

Sources & evidence

ORD record
ord-032132e9635843f996019c67ceeebf46
Source dataset
uspto-grants-1996_05
Patent number
US05519138

Reaction notes

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