Sodium Hydroxide → HCID 178467364, compound

HRID 440608Notes

Reaction equation

HRID 440608 reaction equation
[CH2:1]([O:3][C:4]1[N:8]([CH2:9][C:10]2[CH:15]=[CH:14][C:13]([O:16][CH:17]([C:24]3[NH:28][N:27]=[N:26][N:25]=3)[C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)=[CH:12][CH:11]=2)[C:7]2[C:29]([C:33]([O:35]CC)=[O:34])=[CH:30][CH:31]=[CH:32][C:6]=2[N:5]=1)[CH3:2].[OH-].[Na+]>C(O)C>[CH2:1]([O:3][C:4]1[N:8]([CH2:9][C:10]2[CH:15]=[CH:14][C:13]([O:16][CH:17]([C:24]3[NH:28][N:27]=[N:26][N:25]=3)[C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)=[CH:12][CH:11]=2)[C:7]2[C:29]([C:33]([OH:35])=[O:34])=[CH:30][CH:31]=[CH:32][C:6]=2[N:5]=1)[CH3:2]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 178468772HCID 178468772, compound

Product 1

HCID 178467364HCID 178467364, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Prepared analogously to Example 1b from 2-ethoxy-7-ethoxycarbonyl-1-[4-[α-(1H-tetrazol-5-yl)benzyloxy]benzyl]benzimidazole and 2N sodium hydroxide solution in ethanol.

Sources & evidence

ORD record
ord-1fa8d660b44848f39d7e985e9a14e3ef
Source dataset
uspto-grants-1996_05
Patent number
US05519138

Reaction notes

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