関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Benzene | HCID 241 | — |
| 反応物 | Hydrogen Bromide | HCID 260 | — |
| 反応物 | Phenyl acridine-9-carboxylate | HCID 517916 | — |
| 反応物 | Tert-butyl 3-iodopropanoate | HCID 10400154 | — |
| 溶媒 | Acetic Acid | HCID 176 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 9-Phenoxycarbonyl-10-carboxyethylacridinium bromide | HCID 86749506 | — |
反応手順
A mixture of phenyl acridine-9-carboxylate (100 mg) and t-butyl 3-iodopropionate (5 g) is stirred and heated at 130° C. for sixteen hours. The resulting solution is poured into benzene (25 ml) and the resulting precipitate isolated by filtration. Part of this precipitate (10 mg) is stirred with 33% hydrobromic acid in acetic acid (1 ml), and heated at 50° C. for two hours. The reaction mixture is poured into water, and the resulting precipitate (ca. 6 mg) isolated.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 特許番号 | US05521103 |
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| 出典データセット | uspto-grants-1996_05 |
|---|
| ORD ID | ord-4bbefbaefbe64cddb97d6bc976372e21 |
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| 出典メモ | uspto-grants-1996_05 |
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