HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloro-2,3-dihydro-2,2-dimethyl-7-nitrobenzofuran-3-one → 7-Amino-4-chloro-2,3-dihydro-2,2-dimethylbenzofuran-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloro-2,3-dihydro-2,2-dimethyl-7-nitrobenzofuran-3-one | HCID 22404810 | — |
| Catalyst | Iron | HCID 23925 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Solvent | Water | HCID 962 | — |
| Product | 7-Amino-4-chloro-2,3-dihydro-2,2-dimethylbenzofuran-3-one | HCID 22404723 | 76.8% |
Reaction Steps
By the method of Example 1, Step E, 4.82 g (0.020 mole) of 4-chloro-2,3-dihydro-2,2-dimethyl-7-nitrobenzofuran-3-one and 5.0 g of powdered iron were reacted in 80 mL of glacial acetic acid and 10 mL of water, yielding 3.25 g of 7-amino-4-chloro-2,3-dihydro-2,2-dimethylbenzofuran-3-one as an oil which subsequently solidified, m.p. 71°-73° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05521147 |
| Source dataset | uspto-grants-1996_05 |
| ORD ID | ord-71af8db5ec0c423787fce94d7cbcbc97 |
| Source note | uspto-grants-1996_05 |