反应详情

In a flask 3.77 g (0.015 mole) of ethyl 2,3-dihydro-7-nitrobenzofuran-3-on-2-ylcarboxylate is suspended in 75 mL of a 5% aqueous solution of sodium hydroxide which is heated at reflux until all solid has gone into solution. The solution is cooled to ambient temperature, and dilute sulfuric acid is added cautiously until there is no further evidence of decarboxylation. The product is extracted with ethyl acetate, and the combined extracts are dried over anhydrous magnesium sulfate and filtered. The filtrate is evaporated under reduced pressure, leaving 2,3-dihydro-7-nitro-3-benzofuranone as a residue.

1. temperatureis heated
2. temperatureat reflux until all solid
3. extractionThe product is extracted with ethyl acetate
4. dry with materialthe combined extracts are dried over anhydrous magnesium sulfate
5. filtrationfiltered
6. customThe filtrate is evaporated under reduced pressure