100-31-2 → 4,4'-(Ethane-1,2-diyl)dibenzoic acid

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Reaction Steps

A solution of 0.2 g of (E)-stilbene-4,4'-dicarboxylic acid bis-(2,3,4,5,6-penta-O-sulfo-D-glucit-1-ylamide) decasodium salt (see Example 2) in 15 ml of water was hydrogenated at room temperature for 3 hours in the presence of 10% palladium on charcoal. The catalyst was filtered off and the filtrate was concentrated. The residue was purified over an ion exchange column and gave 4,4'-ethylene-dibenzoic acid bis-(2,3,4,5,6-penta-O-sulfo-D-glucit-1-ylamide) decasodium salt, [α]D20 -4.8° (c 0.4; water), MS: m/z 1616.5 (reconstructed M).

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