Sodium Hydroxide → HCID 54526852, compound

HRID 440857Notes

Reaction equation

HRID 440857 reaction equation
[CH2:1]([C:3]1[N:7]([CH2:8][C:9]2[CH:14]=[CH:13][C:12]([C:15]3[C:16]([C:21]([O:23]C)=[O:22])=[CH:17][CH:18]=[CH:19][CH:20]=3)=[CH:11][CH:10]=2)[C:6]2[CH:25]=[C:26]([NH:30][C:31]3[C:34](=[O:35])[C:33](=[O:36])[C:32]=3[N:37]([CH3:39])[CH3:38])[CH:27]=[C:28]([CH3:29])[C:5]=2[N:4]=1)[CH3:2].[OH-].[Na+]>C(O)C>[CH2:1]([C:3]1[N:7]([CH2:8][C:9]2[CH:14]=[CH:13][C:12]([C:15]3[C:16]([C:21]([OH:23])=[O:22])=[CH:17][CH:18]=[CH:19][CH:20]=3)=[CH:11][CH:10]=2)[C:6]2[CH:25]=[C:26]([NH:30][C:31]3[C:34](=[O:35])[C:33](=[O:36])[C:32]=3[N:37]([CH3:39])[CH3:38])[CH:27]=[C:28]([CH3:29])[C:5]=2[N:4]=1)[CH3:2]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 54235625HCID 54235625, compound

Product 1

HCID 54526852HCID 54526852, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Prepared analogously to Example 1d from methyl 4'-[[2-ethyl-4-methyl-6-[(2-dimethylamino-3,4-dioxo-1-cyclobuten-1-yl) -amino]-1H-benzimidazol-1-yl]-methyl]-biphenyl-2-carboxylate and 1N sodium hydroxide solution in ethanol.

Sources & evidence

ORD record
ord-ae47f779a96d43df83e233a5cb8ad09b
Source dataset
uspto-grants-1996_05
Patent number
US05521177

Reaction notes

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