Sodium Hydroxide → HCID 54556252, compound

HRID 440863Notes

Reaction equation

HRID 440863 reaction equation
[CH2:1]([C:3]1[N:7]([CH2:8][C:9]2[CH:14]=[CH:13][C:12]([C:15]3[C:16]([C:21]([O:23]C)=[O:22])=[CH:17][CH:18]=[CH:19][CH:20]=3)=[CH:11][CH:10]=2)[C:6]2[CH:25]=[C:26]([N:30]([CH3:38])[C:31]([N:35]([CH3:37])[CH3:36])=[N:32][C:33]#[N:34])[CH:27]=[C:28]([CH3:29])[C:5]=2[N:4]=1)[CH3:2].[OH-].[Na+]>C(O)C>[CH2:1]([C:3]1[N:7]([CH2:8][C:9]2[CH:14]=[CH:13][C:12]([C:15]3[C:16]([C:21]([OH:23])=[O:22])=[CH:17][CH:18]=[CH:19][CH:20]=3)=[CH:11][CH:10]=2)[C:6]2[CH:25]=[C:26]([N:30]([CH3:38])[C:31]([N:35]([CH3:37])[CH3:36])=[N:32][C:33]#[N:34])[CH:27]=[C:28]([CH3:29])[C:5]=2[N:4]=1)[CH3:2]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 54060673HCID 54060673, compound

Product 1

HCID 54556252HCID 54556252, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Prepared analogously to Example 1d from methyl 4'-[[2-ethyl-4-methyl-6-(3,3-dimethyl-2-cyano-1-methyl-guanidino) -1H-benzimidazol-1-yl]-methyl]-biphenyl-2-carboxylate and 2N sodium hydroxide solution in ethanol.

Sources & evidence

ORD record
ord-5a73b3256fef452cab1729866223d6c7
Source dataset
uspto-grants-1996_05
Patent number
US05521177

Reaction notes

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