HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloroformamidinium chloride → 2,4-Diamino-6-[1-chloro-2-(4-trifluoromethylphenyl)ethenyl]pteridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloroformamidinium chloride | HCID 3084509 | — |
| Reactant | 2-Amino-3-cyano-5-[(4-trifluoromethylphenyl)ethynyl]pyrazine | HCID 15335274 | — |
| Solvent | Diglyme | HCID 8150 | — |
| Product | 2,4-Diamino-6-[1-chloro-2-(4-trifluoromethylphenyl)ethenyl]pteridine | HCID 54399058 | — |
Reaction Steps
This compound is prepared in a manner analogous to that of Step C of Example 7, using 2.9 grams (0.009 mole) of 2-amino-3-cyano-5-[(4-trifluoromethylphenyl)ethynyl]pyrazine and 0.9 gram (0.009 mole) of chloroformamidine hydrochloride in 20 mL of diglyme, yielding 2,4-diamino-6-[1-chloro-2-(4-trifluoromethylphenyl)ethenyl]pteridine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05521190 |
| Source dataset | uspto-grants-1996_05 |
| ORD ID | ord-4d13f5da4a83453e95e43c801690e9ea |
| Source note | uspto-grants-1996_05 |