HuagongsheHuagongshe Chemistry Print Report · For research reference only
Butylamine → N-[5-(n-butylaminoacetylamino)4-nitro-2-phenoxyphenyl]methanesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Butylamine | HCID 8007 | — |
| Reactant | 1,4-Dioxane | HCID 31275 | — |
| Reactant | N-(5-chloroacetylamino-4-nitro-2-phenoxyphenyl)methanesulfonamide | HCID 15285981 | — |
| Solvent | Water | HCID 962 | — |
| Product | N-[5-(n-butylaminoacetylamino)4-nitro-2-phenoxyphenyl]methanesulfonamide | HCID 15285982 | 72% |
Reaction Steps
To 7 ml of a dioxane solution containing 1.4 g of N-(5-chloroacetylamino-4-nitro-2-phenoxyphenyl)methanesulfonamide was added 0.77 g of n-butylamine at room temperature, followed by stirring for an hour. Water was added to the reaction solution, the precipitate was collected by filtration and recrystallized from ethanol to give 1.1 g of N-[5-(n-butylaminoacetylamino)4-nitro-2-phenoxyphenyl]methanesulfonamide as yellow needles.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05521311 |
| Source dataset | uspto-grants-1996_05 |
| ORD ID | ord-6507560dbca94101bac182f858905b27 |
| Source note | uspto-grants-1996_05 |