N-(5-aminoacetylamino-4-nitro-2-phenoxyphenyl)methanesulfonamide → N-[5-(n-butylaminoacetylamino)4-nitro-2-phenoxyphenyl]methanesulfonamide

HRID 441129Notes

Reaction equation

HRID 441129 reaction equation
[NH2:1][CH2:2][C:3]([NH:5][C:6]1[C:7]([N+:24]([O-:26])=[O:25])=[CH:8][C:9]([O:17][C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)=[C:10]([NH:12][S:13]([CH3:16])(=[O:15])=[O:14])[CH:11]=1)=[O:4]>CC(C)=O>[CH2:7]([NH:1][CH2:2][C:3]([NH:5][C:6]1[C:7]([N+:24]([O-:26])=[O:25])=[CH:8][C:9]([O:17][C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)=[C:10]([NH:12][S:13]([CH3:16])(=[O:14])=[O:15])[CH:11]=1)=[O:4])[CH2:6][CH2:11][CH3:10]

Participants

3

Reactant 1

HCID 22406110N-(5-aminoacetylamino-4-nitro-2-phenoxyphenyl)methanesulfonamide

Product 1

HCID 15285982N-[5-(n-butylaminoacetylamino)4-nitro-2-phenoxyphenyl]methanesulfonamide

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

Following the same procedure as that of Example 23 except for the use of N-(5-aminoacetylamino-4-nitro-2-phenoxyphenyl)methanesulfonamide obtained by the procedure of Example 22 andacetonitrile in place of N-[5-(n-butylaminoacetylamino)-4-nitro-2-phenoxyphenyl]methanesulfonamide and acetone as a reaction solvent used in Example 23, N-(5-aminoacetylamino-4-nitro-2-phenoxyphenyl)methanesulfonamide hydrochloride was obtained.

Sources & evidence

ORD record
ord-cf9cb1ba9250485a96aa7cf5b8dc1fe1
Source dataset
uspto-grants-1996_05
Patent number
US05521311

Reaction notes

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