Sodium Hydroxide → HCID 15337400, compound

Participants

Reaction Steps

A mixture of the product of Step 3 (450 mg), phenylboric acid (750 mg), Pd (PPh3)4 (80 mg) and NaOH (3 mL, 1N) in toluene (8 ml) and EtOH (10 mL) was refluxed for 20 h. A saturated solution of NaHCO3 (50 ml) was added and the mixture was extracted with Et2O (200 mL). The extract was dried over MgSO4 and concentrated. The residue was purified by flash chromatography eluted with 30:1 hexane/EtOAc to give the title compound (300 mg).

Provenance & Evidence