Pyridine → HCID 73885489, compound

Participants

Reaction Steps

A solution of 1-(4-nitrobenzoyl)-2,3,4,5-tetrahydro -1H-2-benzazepin-5-one (465 mg), hydroxylamine hydrochloride (209 mg) and pyridine (237 mg) in ethanol (10 ml) was stirred for 1.5 hours at 90° C. The solvent was evaporated and diluted with ethyl acetate and the solution was washed with successively water and brine. The organic phase was dried over magnesium sulfate and the solvent was evaporated in vacuo to give crude 5-hydroxyimino-1-(4-nitrobenzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepine (500 mg).

Provenance & Evidence