HCID 10848153, compound → HCID 22405139, compound

Participants

Reaction Steps

To a solution of 1-ethoxycarbonylmethyl-1,3,4,5-tetrahydro-1,5-benzodiazepin-2(2H)-one (173 mg) in tetrahydrofuran (5 ml) was added diborane dimethylsulfide complex (10 mol solution, 0.5 ml) and the mixture was stirred at ambient temperature for 8 hours. The solution was washed with water and brine, dried over magnesium sulfate. The solvent was evaporated in vacuo and a residue was purified by silica gel column to give 1-ethoxycarbonylmethyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine (125 mg) as a pale brown oil.

Provenance & Evidence