Acetyl chloride → 1-{4-[2-(2-Methoxycarbonylphenyl)benzoylamino]benzoyl}-1,2,3,4-tetrahydroquinoline

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Reaction Steps

To a solution of acetyl chloride (1 ml) and methanol (20 ml) was added 1-{4-[2-(2-carboxyphenyl)benzoylamino]benzoyl}-1,2,3,4-tetrahydroquinoline (350 mg) at 0° C. The solution was stirred for 30 minutes at the same temperature and then stirred for 3 hours at ambient temperature. The solvent was evaporated in vacuo and triturated from dichloromethane to give 1-{4-[2-(2methoxycarbonylphenyl)benzoylamino]benzoyl}-1,2,3,4tetrahydroquinoline (300 mg).

Provenance & Evidence