反应详情

42 g of diketene were added to a solution of 82.1 g of m-aminopropionanilide in 400 ml of benzene and the mixture was stirred for 41/2 hours and then was vacuum filtered. The recovered precipitate was washed with benzene, then isopropyl ether and dried to obtain 118 g of m-propionamido-acetylacetanilide melting at 70° C. which was used as is for the next step.

1. filtrationfiltered
2. washThe recovered precipitate was washed with benzene
3. dry with materialisopropyl ether and dried