Sulfuric Acid → HCID 21420509, compound

Participants

Reaction Conditions

Reaction Steps

To 34,5 g of 2-acetylamino-2-ethoxycarbonyl-3-oxo-1,2,3,13b-tetrahydro-9H-pyrrolo[1,2-a]-dibenzo[c,f] azepine (oil, Rf in toluene: ethanol (9:2) = 0.5) are added 170 ml water and 10 ml concentrated H2SO4. The mixture is refluxed at 130° C. for 18 hours, then cooled down and made alcaline with KOH. The mixture is extracted wtih methylenechloride and the extracts washed with water, dried and evaporated. Melting point 186°-188° C. Yield 97%.

Provenance & Evidence