Butylamine → HCID 135623124, compound

HRID 441342Notes

Reaction equation

HRID 441342 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8](=O)[CH2:9][S:10]([CH3:12])=[O:11].[CH2:14]([NH2:18])[CH2:15][CH2:16][CH3:17]>>[CH2:14]([N:18]=[C:8]([C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=1[OH:1])[CH2:9][S:10]([CH3:12])=[O:11])[CH2:15][CH2:16][CH3:17]

Participants

3

Reactant 2

HCID 8007ButylamineHCID 578088HCID 578088, compound

Product 1

HCID 135623124HCID 135623124, compoundYield 95%

Procedure

A solution of 2'-hydroxy-2-(methylsulfinyl)acetophenone (15 g, 0.076 mole) in n-butylamine (75 ml) was stirred at room temperature for 16 hrs. The reaction mixture was poured into petroleum ether (500 ml) and the product, which precipitated, was filtered off. Recrystallization from ethylacetate-cyclohexane gave yellow crystals (18.2 g, 95%), mp 128°-129°.

Workup

  1. customthe product, which precipitated
  2. filtrationwas filtered off
  3. customRecrystallization from ethylacetate-cyclohexane

Sources & evidence

ORD record
ord-84792e350263417ba3a2869b3efb6861
Source dataset
uspto-grants-1977_08
Patent number
US04039579

Reaction notes

Loading…