HCID 20324274, compound → HCID 15328860, compound

HRID 441356Notes

Reaction equation

HRID 441356 reaction equation
[Br:1][C:2]1[CH:17]=[CH:16][C:5]([C:6]([CH:14]=[CH2:15])([OH:13])[C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)=[CH:4][CH:3]=1>[Pd].C1C=CC=CC=1>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([C:6]([CH2:14][CH3:15])([OH:13])[C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)=[CH:16][CH:17]=1

Participants

4

Reactant 1

HCID 20324274HCID 20324274, compound

Product 1

HCID 15328860HCID 15328860, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 241BenzeneSolvent

Procedure

0.6 g. of 10% palladium-on-carbon are added to a solution of 29 g. of 4-bromo-α-vinyl-benzhydrol in 300 ml. of benzene, and the mixture is hydrogenated at room temperature under atmospheric pressure. After the uptake of the calculated amount of hydrogen the catalyst is filtered off, and the benzene is evaporated from the clear filtrate under reduced pressure. 25 g. of clear, viscous oil, boiling at 140° C./0.8 mmHg. are obtained as residue.

Workup

  1. customis hydrogenated at room temperature under atmospheric pressure
  2. filtrationAfter the uptake of the calculated amount of hydrogen the catalyst is filtered off
  3. customthe benzene is evaporated from the clear filtrate under reduced pressure
  4. customare obtained as residue

Sources & evidence

ORD record
ord-9b6e8716c47f4f64bde7c0f169181f79
Source dataset
uspto-grants-1977_08
Patent number
US04039589

Reaction notes

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