1,1-Diphenyl-2-propen-1-ol → 1,1-Diphenylpropan-1-ol

HRID 441357노트

반응식

HRID 441357 반응식
[CH:1]([C:3]([OH:16])([C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1)=[CH2:2]>[Pd].C1CCCCC1>[CH2:1]([C:3]([OH:16])([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1)[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)[CH3:2]

참가 물질

4

반응물 1

HCID 111066331,1-Diphenyl-2-propen-1-ol

생성물 1

HCID 2261491,1-Diphenylpropan-1-ol

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 8078Cyclohexane용매

실험 절차

A mixture of 21 g. of α-vinyl-benzhydrol and 84 ml. of cyclohexane is refluxed in the presence of palladium catalyst. When the reaction is over, as evidenced by thin layer chromatography, the mixture is cooled, the catalyst is filtered off, and the filtrate is evaporated under reduced pressure. 21.2 g. of crystalline α-ethyl-benzhydrol, melting at 93°-94° C., are obtained as residue.

후처리

  1. additionA mixture of 21 g
  2. temperaturethe mixture is cooled
  3. filtrationthe catalyst is filtered off
  4. customthe filtrate is evaporated under reduced pressure

출처 및 근거

ORD 기록
ord-4a08e7ea610949bf9f5da655f6cf30ff
출처 데이터셋
uspto-grants-1977_08
특허 번호
US04039589

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