Nitric Acid → HCID 86734982, compound

HRID 441365Notes

Reaction equation

HRID 441365 reaction equation
[CH3:1][CH2:2][CH2:3][CH:4]([CH2:13][C:14]([NH:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)=[O:15])[CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].[N+:23]([O-])([OH:25])=[O:24]>O>[N+:23]([CH:2]([CH2:3][CH:4]([CH2:13][C:14]([NH:16][C:17]1[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=1)=[O:15])[CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12])[CH3:1])([O-:25])=[O:24]

Participants

4

Reactant 2

HCID 944Nitric AcidHCID 53882134HCID 53882134, compound

Product 1

HCID 86734982HCID 86734982, compoundYield 2,435.1%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

4-Dodecylacetanilide (252 g) was added portionwise over 45 minutes to a stirred solution of nitric acid (density 1.50 g. ml.) (210 ml) and water (23 ml) keeping the temperature between 35° and 40° C. The mixture was stirred for a further 30 minutes, drowned into cold water (1200 ml) and the precipitated solid filtered off, washed acid free with water, dried and recrystallised from ethanol to give 202 g of 2-nitro-4-dodecylacetanilide as fine needles, melting at 71°-2° C.

Workup

  1. customthe temperature between 35° and 40° C
  2. filtrationthe precipitated solid filtered off
  3. washwashed acid free with water
  4. customdried
  5. customrecrystallised from ethanol

Sources & evidence

ORD record
ord-91cd73f369cc42c1a578640fe587f312
Source dataset
uspto-grants-1977_08
Patent number
US04039612

Reaction notes

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