Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triethylamine → 8-trifluoromethyl-6-(o-chlorophenyl)-1-[(phthalimidooxy)methyl]-4H-s-triazolo[4,3-a][1,4]benzodiazepine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | N-Hydroxyphthalimide | HCID 10665 | — |
| 반응물 | 8-(trifluoromethyl)-1-(chloromethyl)-6-(o-chlorophenyl)-4H-s-triazolo[4,3-a][1,4]benzodiazepine | HCID 21330780 | — |
| 용매 | Dimethylacetamide | HCID 31374 | — |
| 생성물 | 8-trifluoromethyl-6-(o-chlorophenyl)-1-[(phthalimidooxy)methyl]-4H-s-triazolo[4,3-a][1,4]benzodiazepine | HCID 20361249 | — |
반응 단계
In the manner given in Example 1, N-hydroxyphthalimide and triethylamine in dimethylacetamide is treated with 8-trifluoromethyl-6-(o-chlorophenyl)-1-(chloromethyl)-4H-s-triazolo[4,3-a][1,4]benzodiazepine to give 8-trifluoromethyl-6-(o-chlorophenyl)-1-[(phthalimidooxy)methyl]-4H-s-triazolo[4,3-a][1,4]benzodiazepine.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04039551 |
| 출처 데이터셋 | uspto-grants-1977_08 |
| ORD ID | ord-dcc604fcec5a413795bf801ea1dcaf38 |
| 출처 메모 | uspto-grants-1977_08 |