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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 441416Generated: October 31, 2026

Ethanol → 2-(4-Phenoxymethylphenoxy)-propionic acid

https://huagongshe.com/reaction/441416

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanolHCID 702—
ReactantWaterHCID 962—
ReactantPotassium HydroxideHCID 14797—
Reactant2-(4-Phenoxymethylphenoxy)-propionitrileHCID 21421164—
Product2-(4-Phenoxymethylphenoxy)-propionic acidHCID 21421173—

Reaction Steps

One gram of 2-(4-phenoxymethylphenoxy)-propionitrile (obtainable from 4-phenoxymethylphenol and 2-bromopropionitrile) is refluxed in 15 ml. of ethanol and 2 ml. of water with 2 g. of KOH for 40 hours. The mixture is then evaporated and worked up as usual, yielding 2-(4-phenoxymethylphenoxy)-propionic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04039683
Source datasetuspto-grants-1977_08
ORD IDord-c1808875d626473b89e4a6d9823fa7b5
Source noteuspto-grants-1977_08