反应详情

A mixture of 50.0 g of cyclohexene oxide and 100 ml of 25 percent aqueous dimethylamine was heated with stirring at 145° in a small autoclave for 8 hours. While the mixture was being concentrated to dryness at 50° on a film evaporator, absolute ethanol was added periodically to aid in removal of water. The residue was distilled through a Nester-Faust spinning band column to give 53.0 g of 2-dimethylamino-1-cyclohexanol, b.p. 64.1 - 64.2/2.4 mm. The ir curve was consistent with the assigned structure.

1. temperaturewas heated
2. concentrationWhile the mixture was being concentrated to dryness at 50° on a film evaporator, absolute ethanol
3. additionwas added periodically
4. customto aid in removal of water
5. distillationThe residue was distilled through a Nester-Faust