Toluene → Toluene dimethoxyethane

Participants

Reaction Steps

A saturated solution of compound of formula (I), Form VI in 1,2-dimethoxyethane was made at room temperature by adding 1.4 mL of 1,2-dimethoxyethane to approximately 698 mg of Form VI. The saturated solution was stirred for approximately 1 h and subsequently filtered through a filter of 0.45 μm pore size. A reverse addition of 200 μL of the as prepared saturated solution was added at once to 800 μL of toluene acting as anti-solvent. After precipitation the solid material was separated from solution and analyzed as described in Table 1. No drying under vacuum was applied prior to the analyses.

Provenance & Evidence