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Methyl 2-methyl-3-(phenylmethoxy)propanoate → 3-Benzyloxy-2-methylpropan-1-ol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methyl 2-methyl-3-(phenylmethoxy)propanoate | HCID 13531536 | — |
| 反応物 | Sodium bis(2-methoxyethoxy)aluminiumhydride | HCID 21584525 | — |
| 生成物 | 3-Benzyloxy-2-methylpropan-1-ol | HCID 562208 | 90.5% |
反応手順
Reduction of the rac.-methyl-3-benzyloxy-2-methylpropionate was carried out with sodium bis(2-methoxyethoxy)-aluminum hydride using the procedure described in Example 9. Distillation of the crude product afforded the rac. 3-benzyloxy-2-methyl-1-propanol in 90.5% yield as a colorless liquid, b.p. 94°-98° C. (0.1 mm Hg.).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04041058 |
| 出典データセット | uspto-grants-1977_08 |
| ORD ID | ord-1ba07ab022f7429c932a7b58e0466687 |
| 出典メモ | uspto-grants-1977_08 |