L-Glutamic Acid → HCID 86734995, compound

Participants

Reaction Steps

Amphotericin B methyl ester (9.36 g, 0.01 Mol) is added in portions to a solution of L-glutamic acid (0.81 g, 0.0055 Mol) in 500 ml of water and stirred until complete dissolution (1 hour). The clear solution is then lyopholized. The yield is 88.9%. The product is soluble in water even at concentrations of 10% at RT and when dissolved in water to form a 1% solution is found to have a pH of 6.02.

Provenance & Evidence