L-Aspartic Acid → HCID 86734996, compound

Participants

Reaction Steps

Amphotericin B methyl ester (9.36 g, 0.01 Mol) is added in portions to a solution of L-aspartic acid (0.73 g, 0.0055 Mol) in 500 ml of water and stirred until dissolution (1 hour). The clear solution is thereafter freeze-dried. The product when dissolved in water (1%) has a pH of 6.25 and a solubility of greater than 10% at RT.

Provenance & Evidence