Methyl iodide → Hydrazine

HRID 441681Notes

Reaction equation

HRID 441681 reaction equation
[IH:1].[C:2]1([CH:8]2[CH2:12][NH:11][C:10]([NH:13][NH2:14])=[N:9]2)[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C1(C2CN[C:23](=[S:26])N2)C=CC=CC=1.CI>C(O)C>[IH:1].[CH3:23][S:26][C:10]1[NH:11][CH2:12][CH:8]([C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)[N:9]=1.[NH2:13][NH2:14]

Participants

6

Reactant 3

HCID 6328Methyl iodideHCID 13158511HCID 13158511, compoundHCID 178506608HCID 178506608, compound

Product 2

HCID 9321HydrazineHCID 178503382HCID 178503382, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The starting material, 4-phenyl-2-imidazolin-2-ylhydrazine hydroiodide, is prepared as follows: 4-phenylimidazolidine-2-thione and methyliodide in refluxing ethanol yield 2-methylthio-4-phenyl-2-imidazolin hydroiodide, which upon treatment with hydrazine in boiling ethanol yields the desired intermediate, melting at 107°-108° C.

Sources & evidence

ORD record
ord-b7354330705c463e83aaf7dcd5772b3c
Source dataset
uspto-grants-1977_08
Patent number
USRE029358

Reaction notes

Loading…