Hydrazine → (4,5,6,7-Tetrahydro-1H-[1,3]diazepin-2-yl)-hydrazine

HRID 441685Notes

Reaction equation

HRID 441685 reaction equation
Cl.[NH:2]1[CH2:8][CH2:7][CH2:6][CH2:5][N:4]=[C:3]1[NH:9][NH2:10].CSC1NCCCCN=1.NN>C(O)C>[NH:4]1[CH2:5][CH2:6][CH2:7][CH2:8][N:2]=[C:3]1[NH:9][NH2:10]

Participants

5

Reactant 3

HCID 9321HydrazineHCID 2011542-(methylthio)-4,5,6,7-tetrahydro-1H-1,3-diazepineHCID 21417092(4,5,6,7-Tetrahydro-1H-[1,3]diazepin-2-yl)-hydrazine hydrochloride

Product 1

HCID 13194083(4,5,6,7-Tetrahydro-1H-[1,3]diazepin-2-yl)-hydrazine

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The starting material, 4,5,6,7-tetrahydro-1H-1,3-diazepin-2-ylhydrazine hydrochloride, is prepared as follows: 4,5,6,7-tetrahydro-2-methylthio-1H-1,3-diazepine (McKay and Kreling. Can. J. Chem. 35 1438 (1957) and hydrazine are added to ethanol, and the solution then heated to yield 4,5,6,7-tetrahydro-1H-1,3-diazepin-2-ylhydrazine hydroidide, melting point 133° -135° C. If the latter compound is treated with silver chloride in aqueous or ethanol solution, the hydrochloride salt is obtained, melting point 192°-193° C.

Workup

  1. temperaturethe solution then heated

Sources & evidence

ORD record
ord-ca7abe6b9f384d0eb92a826f211fd7db
Source dataset
uspto-grants-1977_08
Patent number
USRE029358

Reaction notes

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