HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphorus oxychloride → HCID 20528944, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | HCID 20528937 | HCID 20528937 | — |
| Reactant | Sodium Nitrite | HCID 23668193 | — |
| Reactant | HCID 178493785 | HCID 178493785 | — |
| Product | HCID 20528944 | HCID 20528944 | — |
Reaction Steps
The 2-amino substituent of Step A product when treated with sodium nitrite as described in Step E of Preparation 81 is converted to the 2-hydroxy group. Treatment of the 2-hydroxy-3-phenoxy-6-methoxypyrazine with phosphorus oxychloride by the method of Preparation 13, Step B, gives 2-chloro-3-phenoxy-6-methoxypyrazine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04042586 |
| Source dataset | uspto-grants-1977_08 |
| ORD ID | ord-67b6f262b84a42cfac5fd17862f7aaf7 |
| Source note | uspto-grants-1977_08 |