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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 441747Generated: October 30, 2026

Morpholine → 5-Bromo-3-morpholinopyrazin-2-amine

https://huagongshe.com/reaction/441747

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMorpholineHCID 8083—
Reactant2-Amino-3,5-dibromopyrazineHCID 620004—
Product5-Bromo-3-morpholinopyrazin-2-amineHCID 16740441—

Reaction Steps

2-Amino-3,5-dibromopyrazine is reacted with morpholine at 130° C. under pressure yielding 2-amino-3-morpholino-5-bromopyrazine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04042586
Source datasetuspto-grants-1977_08
ORD IDord-d2547d7201ee40549ab642d051401f39
Source noteuspto-grants-1977_08