4-(Dimethylamino)Benzaldehyde → [4-(Dimethylamino)phenyl][4-(trimethylsilyl)phenyl]methanone

HRID 441795Notes

Reaction equation

HRID 441795 reaction equation
[CH3:1][N:2]([CH3:21])[C:3]1[CH:20]=[CH:19][C:6]([CH:7]([OH:18])[C:8]2[CH:13]=[CH:12][C:11]([Si:14]([CH3:17])([CH3:16])[CH3:15])=[CH:10][CH:9]=2)=[CH:5][CH:4]=1.CN(C)C1C=CC(C=O)=CC=1.C[Si](C)(C)C1C=CC(Cl)=CC=1.O=[Cr](=O)(O[Cr](=O)([O-])=O)[O-].[NH+]1C=CC=CC=1.[NH+]1C=CC=CC=1>>[CH3:1][N:2]([CH3:21])[C:3]1[CH:4]=[CH:5][C:6]([C:7]([C:8]2[CH:13]=[CH:12][C:11]([Si:14]([CH3:16])([CH3:15])[CH3:17])=[CH:10][CH:9]=2)=[O:18])=[CH:19][CH:20]=1

Participants

5

Reactant 4

HCID 74794-(Dimethylamino)BenzaldehydeHCID 66351(p-Chlorophenyl)trmethylsilaneHCID 2724130Cornforth reagentHCID 21417838HCID 21417838, compound

Product 1

HCID 19964147[4-(Dimethylamino)phenyl][4-(trimethylsilyl)phenyl]methanone

Procedure

4-Dimethylamino-4'-trimethylsilylbenzhydrol prepared from 4-dimethylaminobenzaldehyde and 4-trimethylsilylchlorobenzene was oxidized by a Cornforth reagent, to yield 4-dimethylamino-4'-trimethylsilyl benzophenone.

Sources & evidence

ORD record
ord-702b3562457642fd8c45b8f72af809d9
Source dataset
uspto-grants-1977_08
Patent number
US04042613

Reaction notes

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