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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 441818Generated: October 26, 2026

Benzene, 1-iodo-3-(trifluoromethyl)- → 5-methyl-1(3'-trifluoromethylphenyl)-2-(1H)-pyridone

https://huagongshe.com/reaction/441818

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzene, 1-iodo-3-(trifluoromethyl)-HCID 67868—
Reactant2-Hydroxy-5-methylpyridineHCID 70482—
Product5-methyl-1(3'-trifluoromethylphenyl)-2-(1H)-pyridoneHCID 983791178%

Reaction Steps

The reaction of 5-methyl-2- (1H)-pyridone with -3-trifluoromethyl-iodobenzene by the procedure of Example 1, gives a 78% yield of 5-methyl-1-(3'-trifluoromethylphenyl)-2-(1H)-pyridone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04042699
Source datasetuspto-grants-1977_08
ORD IDord-7e768e98bfbb46bf90c0155fececd694
Source noteuspto-grants-1977_08