Methyl iodide → HCID 21418367, compound

Participants

Reaction Steps

To a solution of 14 g of 3-(p-chlorophenyl)-1H-benz[f] indazole dissolved in 150 ml. dry dimethylacetamide under nitrogen is added 3 g. of a 57% suspension of sodium hydride in mineral oil. The reaction mixture is stirred at room temperature for 1 hour and then 5 ml. of methyl iodide is added. Stirring is continued for 2 hours then the mixture is poured on ice-water, and the precipitate recovered by filtration. The precipitate is recrystallized from ether to yeild the title compound, m.p. 157°-159°.

Provenance & Evidence