HCID 21416630, compound → HCID 21416627, compound

HRID 442108Notes

Reaction equation

HRID 442108 reaction equation
Cl[C:2]1[N:7]=[C:6]([CH3:8])[N:5]=[C:4]2[N:9]([CH3:20])[N:10]=[C:11]([C:12]3[O:13][C:14]([N+:17]([O-:19])=[O:18])=[CH:15][CH:16]=3)[C:3]=12.ClC1N=C[N:25]=C2N(C)N=C(C3OC([N+]([O-])=O)=CC=3)C=12>>[NH2:25][C:2]1[N:7]=[C:6]([CH3:8])[N:5]=[C:4]2[N:9]([CH3:20])[N:10]=[C:11]([C:12]3[O:13][C:14]([N+:17]([O-:19])=[O:18])=[CH:15][CH:16]=3)[C:3]=12

Participants

3

Reactant 2

HCID 21416630HCID 21416630, compoundHCID 21416634HCID 21416634, compound

Product 1

HCID 21416627HCID 21416627, compound

Procedure

The procedure described in Example 3b was repeated using 4-chloro-1,6-dimethyl-3-(5-nitro-2-furyl)-1H-pyrazolo[3,4-d]pyrimidine as starting material instead of 4-chloro-1-methyl-3-(5-nitro-2-furyl)-1H-pyrazolo[3,4-d]pyrimidine, the reaction conditions being the same. The crystalline product was collected, washed with water and dried. Recrystallisation from dimethyl formamide gave 4-amino-1,6-dimethyl-3-(5-nitro-2-furyl)-1H-pyrazolo[3,4-d]pyrimidine having decomposition point > 300° C. identical with the product obtained in Example 2.

Workup

  1. customthe reaction conditions
  2. customThe crystalline product was collected
  3. washwashed with water
  4. customdried
  5. customRecrystallisation from dimethyl formamide

Sources & evidence

ORD record
ord-0ccc98b505be4b9d96877376fb545d10
Source dataset
uspto-grants-1977_08
Patent number
US04044130

Reaction notes

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