HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → HCID 21416534, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | HCID 19362136 | HCID 19362136 | — |
| Reactant | HCID 21416539 | HCID 21416539 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 21416534 | HCID 21416534 | — |
Reaction Steps
Treat the diethylacetal of 2-hydroxy-4-aminobutanal with acetic anhydride in pyridine followed by treatment of the resulting diethylacetal of 2-acetoxy-4-acetamidobutanal with sodium hydride and methyl iodide to obtain the diethylacetal of 2-acetoxy-4-(N-methylacetamido)butanal. Remove the acetal protecting group by means of acid to obtain 2-acetoxy-4-(N-methylacetamido)butanal.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04044123 |
| Source dataset | uspto-grants-1977_08 |
| ORD ID | ord-6a6d7c26feda455286fa8f6ff54919d0 |
| Source note | uspto-grants-1977_08 |