HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → (Z)-Benzyl 3-aminobut-2-enoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Benidipine Impurity 20 | HCID 46861786 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | (Z)-Benzyl 3-aminobut-2-enoate | HCID 5368345 | 75% |
Reaction Steps
Analogously to Example 1 heating a solution of 75 mmols of 3'-nitrobenzylideneacetoacetic acid methyl ester and 75 mmols of β-aminocrotonic acid benzyl ester in 120 ml of pyridine for 10 hours gave 2,6-dimethyl-3-methoxycarbonyl-4-(3'-nitrophenyl)-1,4-dihydropyridine-5-carboxylic acid benzyl ester of melting point 133° C (from ethanol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04044141 |
| Source dataset | uspto-grants-1977_08 |
| ORD ID | ord-a87ac70b104f48f7a09000f94afd8e5a |
| Source note | uspto-grants-1977_08 |