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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 442176Generated: October 30, 2026

Ethanol → (Z)-Benzyl 3-aminobut-2-enoate

https://huagongshe.com/reaction/442176

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanolHCID 702—
Reactant1,4-Dihydropyridine-5-carboxylic acid benzyl esterHCID 86735025—
Product(Z)-Benzyl 3-aminobut-2-enoateHCID 536834575%

Reaction Steps

Analogously to Example 1 heating a solution of 75 mmols of 2'-trifluoromethylbenzylideneacetoacetic acid methyl ester and 75 mmols of β-aminocrotonic acid benzyl ester in 120 ml of ethanol gave 2,6-dimethyl-3-methoxycarbonyl-4-'2'-trifluoromethylphenyl)-1,4-dihydropyridine-5-carboxylic acid benzyl ester of melting point 136° C (from ethanol).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04044141
Source datasetuspto-grants-1977_08
ORD IDord-0f539f2ed3974b48814f115f377bce61
Source noteuspto-grants-1977_08