HCID 68121646, compound → HCID 13673470, compound

HRID 442185Notes

Reaction equation

HRID 442185 reaction equation
[F:1][C:2]([F:35])([F:34])[C:3]1[CH:33]=[CH:32][C:6]([CH2:7][O:8][C:9]([C:11]2[CH:12]([C:23]3[CH:28]=[CH:27][CH:26]=[CH:25][C:24]=3[N+:29]([O-:31])=[O:30])[C:13]([C:19]([O:21]C)=O)=C(C)[NH:15][C:16]=2[CH3:17])=[O:10])=[CH:5][CH:4]=1>C(O)C>[CH3:7][O:8][C:9]([CH2:11][C:19](/[CH:13]=[CH:12]/[C:23]1[C:24]([N+:29]([O-:31])=[O:30])=[CH:25][CH:26]=[CH:27][CH:28]=1)=[O:21])=[O:10].[F:1][C:2]([F:34])([F:35])[C:3]1[CH:4]=[CH:5][C:6]([CH2:7][O:8][C:9](=[O:10])/[CH:11]=[C:16](\[NH2:15])/[CH3:17])=[CH:32][CH:33]=1

Participants

4

Reactant 1

HCID 68121646HCID 68121646, compound

Product 2

HCID 13673470HCID 13673470, compoundHCID 70593900HCID 70593900, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent2×

Procedure

Analogously to Example 1 heating a solution of 75 mmols of 2'-nitrobenzylideneacetoacetic acid methyl ester and 75 mmols of β-aminocrotonic acid 4-trifluoromethylbenzyl ester in 120 ml of ethanol gave 2,6-dimethyl-3-methoxycarbonyl-4-(2'-nitrophenyl)-1,4-dihydropyridine-5-carboxylic acid 4-trifluoromethylbenzyl ester of melting point 130° C (from ethanol).

Sources & evidence

ORD record
ord-403891e8027e4a9ca3268ec41b52fc38
Source dataset
uspto-grants-1977_08
Patent number
US04044141

Reaction notes

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