HCID 86735031, compound → HCID 10752272, compound

HRID 442193Notes

Reaction equation

HRID 442193 reaction equation
[N+:1]([C:4]1[CH:34]=[CH:33][C:7]([CH2:8][O:9][C:10]([C:12]2[CH:13]([C:24]3[CH:29]=[CH:28][CH:27]=[CH:26][C:25]=3[N+:30]([O-:32])=[O:31])[C:14]([C:20]([O:22]C)=O)=C(C)[NH:16][C:17]=2[CH3:18])=[O:11])=[CH:6][CH:5]=1)([O-:3])=[O:2]>C(O)C>[CH3:8][O:9][C:10]([CH2:12][C:20](/[CH:14]=[CH:13]/[C:24]1[C:25]([N+:30]([O-:32])=[O:31])=[CH:26][CH:27]=[CH:28][CH:29]=1)=[O:22])=[O:11].[N+:1]([C:4]1[CH:34]=[CH:33][C:7]([CH2:8][O:9][C:10](=[O:11])/[CH:12]=[C:17](\[NH2:16])/[CH3:18])=[CH:6][CH:5]=1)([O-:3])=[O:2]

Participants

4

Reactant 1

HCID 86735031HCID 86735031, compound

Product 2

HCID 10752272HCID 10752272, compoundHCID 13673470HCID 13673470, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent2×

Procedure

Analogously to Example 1 heating a solution of 75 mmols of 2'-nitrobenzylideneacetoacetic acid methyl ester and 75 mmols of β-aminocrotonic acid 4-nitrobenzyl ester in 120 ml of ethanol gave 2,6-dimethyl-3-methoxycarbonyl-4-(2'-nitrophenyl)-1,4-dihydropyridine-5-carboxylic acid 4-nitrobenzyl ester of melting point 156° C (from ethanol).

Sources & evidence

ORD record
ord-dbf117ae57284d8a97cd92bfff12fbcf
Source dataset
uspto-grants-1977_08
Patent number
US04044141

Reaction notes

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