HCID 68121517, compound → HCID 13673470, compound

HRID 442195Notes

Reaction equation

HRID 442195 reaction equation
[CH3:1][CH:2]([O:9][C:10]([C:12]1[CH:13]([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][C:25]=2[N+:30]([O-:32])=[O:31])[C:14]([C:20]([O:22]C)=O)=C(C)[NH:16][C:17]=1[CH3:18])=[O:11])[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1>C(O)C>[CH3:2][O:9][C:10]([CH2:12][C:20](/[CH:14]=[CH:13]/[C:24]1[C:25]([N+:30]([O-:32])=[O:31])=[CH:26][CH:27]=[CH:28][CH:29]=1)=[O:22])=[O:11].[CH3:1][CH:2]([O:9][C:10](=[O:11])/[CH:12]=[C:17](\[NH2:16])/[CH3:18])[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1

Participants

4

Reactant 1

HCID 68121517HCID 68121517, compound

Product 2

HCID 13673470HCID 13673470, compoundHCID 86735032HCID 86735032, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent2×

Procedure

Analogously to Example 1 heating a solution of 75 mmols of 2'-nitrobenzylideneacetoacetic acid methyl ester and 75 mmols of β-aminocrotonic acid α-methylbenzyl ester in 120 ml of ethanol gave 2,6-dimethyl-3-methoxycarbonyl-4- (2'-nitrophenyl)-1,4-dihydropyridine-5-carboxylic acid α-methylbenzyl ester of melting point 154° C (from ethanol).

Sources & evidence

ORD record
ord-098cbed3e21446779b7809bc5604e08d
Source dataset
uspto-grants-1977_08
Patent number
US04044141

Reaction notes

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