4-Nitro-2',3',4',5',6'-pentafluorobiphenyl → 2',3',4',5',6'-Pentafluoro[1,1'-biphenyl]-4-ylamine

HRID 442268Notes

Reaction equation

HRID 442268 reaction equation
[F:1][C:2]1[C:7]([F:8])=[C:6]([F:9])[C:5]([F:10])=[C:4]([F:11])[C:3]=1[C:12]1[CH:17]=[CH:16][C:15]([N+:18]([O-])=O)=[CH:14][CH:13]=1.[F:21][C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][C:23]=1[C:28]1[CH:33]=[CH:32][C:31]([N+:34]([O-])=O)=[CH:30][CH:29]=1.[F:37][C:38]1[CH:43]=[CH:42][C:41]([C:44]2[CH:49]=[CH:48][C:47]([N+:50]([O-])=O)=[CH:46][CH:45]=2)=[CH:40][C:39]=1[O:53][CH3:54].FC1C=CC(C2C=CC([N+]([O-])=O)=CC=2)=C(OC)C=1>>[F:1][C:2]1[C:3]([C:12]2[CH:17]=[CH:16][C:15]([NH2:18])=[CH:14][CH:13]=2)=[C:4]([F:11])[C:5]([F:10])=[C:6]([F:9])[C:7]=1[F:8].[F:21][C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][C:23]=1[C:28]1[CH:33]=[CH:32][C:31]([NH2:34])=[CH:30][CH:29]=1.[F:37][C:38]1[CH:43]=[CH:42][C:41]([C:44]2[CH:49]=[CH:48][C:47]([NH2:50])=[CH:46][CH:45]=2)=[CH:40][C:39]=1[O:53][CH3:54]

Participants

7

Reactant 4

HCID 112547604-Nitro-2',3',4',5',6'-pentafluorobiphenylHCID 214164601-Fluoro-2-methoxy-4-(4-nitrophenyl)benzeneHCID 214164632-Fluoro-4'-nitro-1,1'-biphenylHCID 214164654'-Fluoro-2'-methoxy-4-nitrobiphenyl

Product 3

HCID 159386172',3',4',5',6'-Pentafluoro[1,1'-biphenyl]-4-ylamineHCID 162443412'-Fluoro[1,1'-biphenyl]-4-amineHCID 214164744-(4'-Fluoro-3'-methoxyphenyl)-aniline

Procedure

When b 2', 3', 4', 5', 6'-pentafluoro-4-nitrobiphenyl, 2'-fluoro-4-nitrobiphenyl or 4'-fluoro-3'-methoxy-4-nitrobiphenyl obtained from Example 2 are used in place of 4'-fluoro-2'-methoxy-4-nitrobiphenyl in the above example, there is obtained 4-(pentafluorophenyl)-aniline, 4-(2'-fluorophenyl)-aniline or 4-(4'-fluoro-3'-methoxyphenyl)-aniline.

Sources & evidence

ORD record
ord-05323558673d4890beee14aaab136974
Source dataset
uspto-grants-1977_08
Patent number
US04044049

Reaction notes

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